TY  - JOUR
TI  - Corneal development associated with eyelid opening 
AU  - Zieske, JamesD.
T2  - The International Journal of Developmental Biology
AB  - The development of the cornea as a tissue initiates as early as five weeks in the human embryo. This development continues gradually until the time of eyelid opening, which is 
associated with major developmental changes. These events, most easily observed in rodents, which are born with closed eyelids, include alterations in the rate of cell proliferation in the epithelium, stroma and endothelium; differentiation of the epithelium; appearance of a tear film and tear-film-associated proteins; and swelling and thinning of the stroma. Eyelid opening is also associated with numerous alterations in gene expression. These events are the subject of this review. Readers are directed to the article by Wolosin et al., also in this volume, for an in-depth discussion of early corneal development.
PY  - 2004
DO  - 10.1387/ijdb.041860jz
VL  - 48
IS  - 8-9
SP  - 903
EP  - 911
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/041860jz
Y2  - 2024/05/05/13:07:54
ER  -