TY  - JOUR
TI  - Cellular dynamics and molecular control of the development of organizer-derived cells in quail-chick chimeras 
AU  - Charrier, Jean-Baptiste
AU  - Catala, Martin
AU  - Lapointe, Francoise
AU  - Le-Douarin, Nicole
AU  - Teillet, Marie-Aimee
T2  - The International Journal of Developmental Biology
AB  - Malformations affecting the nervous system in humans are numerous and various in etiology. Many are due to genetic deficiencies or mechanical accidents occurring at early stages of development. It is thus of interest to reproduce such human malformations in animal models. The avian embryo is particularly suitable for researching the role of morphogenetic movements and genetic signaling during early neurogenesis. The last ten years of research with Nicole Le Douarin in the Nogent Institut have brought answers to questions formulated by Etienne Wolff at the beginning of his career, by showing that Hensen's node, the avian organizer, is at the source of all the midline cells of the embryo and ensures cell survival, growth and differentiation of neural and mesodermal tissues.
PY  - 2005
DO  - 10.1387/ijdb.041962jc
VL  - 49
IS  - 2-3
SP  - 181
EP  - 191
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/041962jc
Y2  - 2024/05/18/09:26:12
ER  -