TY  - JOUR
TI  - Retinal ganglion cells: dying to survive
AU  - Guerin, MarcB.
AU  - Mckernan, DeclanP.
AU  - O'Brien, ColmJ.
AU  - Cotter, ThomasG.
T2  - The International Journal of Developmental Biology
AB  - This review examines the maturation of the retinal ganglion cell (RGC) population within the nascent retina. Apoptosis, a form of programmed cell death prevalent throughout the developing central nervous system (CNS), is evident in the growth of RGCs within the ganglion cell layer. These cells provide an accessible and illuminating platform to elucidate the apoptotic pathways present in the developing CNS and the role this form of cell death plays in RGC growth. This article focuses on the seminal stages of RGC development and the role played by neurotrophic factors and apoptosis in this process.
PY  - 2006
DO  - 10.1387/ijdb.062159mg
VL  - 50
IS  - 8
SP  - 665
EP  - 674
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/062159mg
Y2  - 2024/05/01/18:45:44
ER  -