TY  - JOUR
TI  - The chick embryo chorioallantoic membrane as a model for in vivo research on angiogenesis.
AU  - Ribatti, D
AU  - Vacca, A
AU  - Roncali, L
AU  - Dammacco, F
T2  - The International Journal of Developmental Biology
AB  - The chick embryo chorioallantoic membrane (CAM) is an extraembryonic membrane that is commonly used in vivo to study both new vessel formation and its inhibition in response to tissues, cells, or soluble factors. Quantitative or semiquantitative methods may be used to evaluate the amount of angiogenesis and anti-angiogenesis. Thanks to the CAM system, angiogenesis could be investigated in association with normal, inflammatory and tumor tissues, and soluble factors inducing angiogenic or anti-angiogenic effects could be identified. Rabbit cornea provides an alternative in vivo system, but CAM appears to be easier to handle and less expensive. Moreover, CAM can be used with very few limitations.
PY  - 1996
VL  - 40
IS  - 6
SP  - 1189
EP  - 1197
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/9032025
Y2  - 2024/05/05/19:53:48
ER  -